Immune cell line assays
- Reporter assay (e.g. NF-kB-SEAP)
- THP1,Jurkat,TF-1, Raji cell cytokine release, proliferation
TAK-242 Specific Inhibition toTLR4 but not TLR2 in NF-kB Reporter Cells
The cpd shows specific inhibition against TLR4 but not TLR2 in TLR4- or TLR2-NF-kB-SEAP reporter cell lines Percentage of inhibition upon LPS
- Service Overview
- Discovery Chemistry
- Biology & Pharmacology
- DMPK / Exploratory Toxicology
- Biologics Discovery
- Biologics CMC
- Small Molecule CMC