Immune profiling for MOA
- Rat CIA synovial fluid cytokine measurement
- Asthma BAL fluid cytokine measurement and FACS
- EAE splenocyte antigen recall
- Tissue Immune profiling by IHC
- Tumor infiltrate lymphocytes (TILs) by IHC or FACS
- Tumor-draining lymph nodes by FACS
DTH and PMA in vivo Models to test Cpds in anti-inflammation
DTH Ear Edema PMA Ear Edema
7 days after painting oxazolone on shaved mouse abdominal skin, the same antigen was painted on the mouse’s right ear
Cytokines from Tissues of DTH or PMA upon Dex or cpdC