Medicinal Chemistry (Associate) Director

Responsibilities

• This position will require the candidate to possess and leverage deep knowledge and capabilities to deliver pre-clinical or clinical candidates. The senior chemist will partner with key scientists in the field of oncology and immunology etc., represent medicinal chemistry on cross-functional project teams, and be co-responsible for building, managing, and delivering projects to meet client needs.
• As a chemistry leader, drive and direct medicinal chemistry functions for one or more drug discovery projects. The main job functions include:
• Working in concert with partners in molecular and cellular biology, pharmacology, ADME, structural biology, chemical development, and other key functions
• Analyze screening data, perform literature reviews, design, propose, and execute medicinal chemistry plans, coordinate chemistry and biology data to support compound progression and patent strategies
• Participate in shaping and implementing strategies that support Medicinal Chemistry growth objectives
• Serve as a scientific expert in medicinal chemistry and provide recommendations regarding new targets and emerging external opportunities
• Ensure optimal interaction/communication and provide updates on project status to clients.
• Direct Reports: Principle Scientist PhD leaders managing the Medicinal Chemistry research areas, Senior Scientists, Associates
• Works closely with Chemistry Department Head providing recommendations to annual budget
• Approves purchase orders of chemicals and lab materials for project teams

Qualifications

• PhD in synthetic or medicinal chemistry is required, preferably with postdoctoral experience
• At least 6+ years of experience in the biotechnology or pharmaceutical industry with a proven track record of innovative projects and key contributions to clinical candidate selection
• Broad experience and proven accomplishments in a field of Medicinal Chemistry, preferably in one or more fields of oncology and immunology, with operational skills for managing discovery programs at the level of a team leader
• Candidates will have a track record of successful contributions to, and leadership of, innovative drug discovery projects, exemplified by a record of patent inventorship, conference presentation and peer-reviewed publication
• Expert knowledge of modern methods of synthetic and medicinal chemistry with ability to successfully and simultaneously conduct medicinal chemistry on multiple projects is required
• Solid understanding of cellular /molecular biology, biochemistry, disease pharmacology, mechanisms of drug metabolism and molecular toxicology, pharmaco-kinetic and pharmaco-dynamic sciences, and the formulations for the in vivo evaluation of drug candidates is required
• Strong knowledge of computational chemistry methods and working knowledge of biophysical methods such as X-ray crystallography and macromolecular NMR is required
• Candidate must have demonstrated influence, negotiation, and conflict resolution skills, including the ability to succeed as a team player
• ●trong oral and written communications skills in English. Fluent in Chinese is a plus but not required.Skills
• Leadership – Clarifying Goals/Objectives; Delegating; Monitoring Work; Motivating and Inspiring Others; Developing and Mentoring
• Management – Strategic Planning; Preparing and Evaluating Budgets; Managing Conflict and Teambuilding
• Science – Using scientific rationales, rules and methods to solve problems.
• Critical Thinking – Using logic and reasoning to identify the strengths and weaknesses of alternative solutions, conclusions or approaches to problems.
• Writing – Communicating effectively in writing as appropriate for the needs of the audience.
• Active Learning – Understanding the implications of new information for both current and future problem-solving and decision-making.
• udgment and Decision Making – Considering the relative costs and benefits of potential actions to choose the most appropriate one.
• Reading Comprehension – Understanding written sentences and paragraphs in scientific related documents.
• Written and Oral Expression – Communicating information and ideas in writing or in speaking so others will understand. Good English communication ability.
• Creativity – Ability to come up with unusual or clever ideas about a given topic or situation, or to develop creative ways to solve a problem.

Location: ZJ Hi-tech Park,Shanghai, China