Medicinal Chemistry (Associate) Director

Responsibilities

  • This position will require the candidate to possess and leverage deep knowledge and capabilities to deliver pre-clinical or clinical candidates. The senior chemist will partner with key scientists in the field of oncology and immunology etc., represent medicinal chemistry on cross-functional project teams, and be co-responsible for building, managing, and delivering projects to meet client needs.
  • As a chemistry leader, drive and direct medicinal chemistry functions for one or more drug discovery projects. The main job functions include:
  • Working in concert with partners in molecular and cellular biology, pharmacology, ADME, structural biology, chemical development, and other key functions
  • Analyze screening data, perform literature reviews, design, propose, and execute medicinal chemistry plans, coordinate chemistry and biology data to support compound progression and patent strategies
  • Participate in shaping and implementing strategies that support Medicinal Chemistry growth objectives
  • Serve as a scientific expert in medicinal chemistry and provide recommendations regarding new targets and emerging external opportunities
  • Ensure optimal interaction/communication and provide updates on project status to clients.
  • Direct Reports: Principle Scientist PhD leaders managing the Medicinal Chemistry research areas, Senior Scientists, Associates
  • Works closely with Chemistry Department Head providing recommendations to annual budget
  • Approves purchase orders of chemicals and lab materials for project teams

Qualifications

  • PhD in synthetic or medicinal chemistry is required, preferably with postdoctoral experience
  • At least 6+ years of experience in the biotechnology or pharmaceutical industry with a proven track record of innovative projects and key contributions to clinical candidate selection
  • Broad experience and proven accomplishments in a field of Medicinal Chemistry, preferably in one or more fields of oncology and immunology, with operational skills for managing discovery programs at the level of a team leader
  • Candidates will have a track record of successful contributions to, and leadership of, innovative drug discovery projects, exemplified by a record of patent inventorship, conference presentation and peer-reviewed publication
  • Expert knowledge of modern methods of synthetic and medicinal chemistry with ability to successfully and simultaneously conduct medicinal chemistry on multiple projects is required
  • Solid understanding of cellular /molecular biology, biochemistry, disease pharmacology, mechanisms of drug metabolism and molecular toxicology, pharmaco-kinetic and pharmaco-dynamic sciences, and the formulations for the in vivo evaluation of drug candidates is required
  • Strong knowledge of computational chemistry methods and working knowledge of biophysical methods such as X-ray crystallography and macromolecular NMR is required
  • Candidate must have demonstrated influence, negotiation, and conflict resolution skills, including the ability to succeed as a team player
  • ●trong oral and written communications skills in English. Fluent in Chinese is a plus but not required.Skills
  • Leadership – Clarifying Goals/Objectives; Delegating; Monitoring Work; Motivating and Inspiring Others; Developing and Mentoring
  • Management – Strategic Planning; Preparing and Evaluating Budgets; Managing Conflict and Teambuilding
  • Science – Using scientific rationales, rules and methods to solve problems.
  • Critical Thinking – Using logic and reasoning to identify the strengths and weaknesses of alternative solutions, conclusions or approaches to problems.
  • Writing – Communicating effectively in writing as appropriate for the needs of the audience.
  • Active Learning – Understanding the implications of new information for both current and future problem-solving and decision-making.
  • udgment and Decision Making – Considering the relative costs and benefits of potential actions to choose the most appropriate one.
  • Reading Comprehension – Understanding written sentences and paragraphs in scientific related documents.
  • Written and Oral Expression – Communicating information and ideas in writing or in speaking so others will understand. Good English communication ability.
  • Creativity – Ability to come up with unusual or clever ideas about a given topic or situation, or to develop creative ways to solve a problem.

Location: ZJ Hi-tech Park,Shanghai, China

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1F & 3F, Block A
2829 JinKe Road
Zhangjiang Hi-Tech Park
PuDong New Area
Shanghai China, 201203

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