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DMPK / Exploratory Toxicology

Home DMPK / Exploratory Toxicology

DMPK / Exploratory Toxicology

ChemPartner’s Drug Metabolism Pharmacokinetic and Exploratory Toxicoly group (DMPK&Expl. Tox)consists of Bioanalytical (GLP and non-GLP), in vitro ADME, Pharmacokinetics and Toxicology groups. Our leadership team, drawing on Pharma experiences from world-renowned companies, emphasizes a science-based culture, and execution of quality DMPK/Toxicology studies as well as the integration of DMPK/Toxicology data into Pharma & Biotech partners’ discovery programs. ChemPartner also conducts studies for many Pharma and Biotech clients in support of their Regulatory Filings.

Since founded in 2007, extensive ADME profiling (>80,000) and PK& Exploratory Toxicology studies (>10,000) have been conducted to support numerous drug discovery and development programs with worldwide partners. Working closely with internal Biology, Pharmacology and Antibody Engineering teams, ChemPartner DMPK group supports translational medicine through our expertise in formulation development, in vitro-in vivo extrapolation, PK/PD modeling, biomarker analysis and metabolomics. We take pride in our work and view our partners’ success as our success.

Our Services:

  • DMPK / Exploratory Toxicology
  • Biomarkers, Preclinical & Clinical Sample Bioanalysis
  • Large molecule PK/BA services

 

  • Service Overview
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      • OncoCP Database
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      • Histopathology
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      • Primary immune cell assays
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      • Volume Discount Fast services for Neuroscience
      • Behavioral Pharmacology
      • In vivo Pain Models
      • Non-Human Primate Cognition
      • In Vitro Electrophysiology
    • Cell Biology
      • Target Validation
      • Cell-based Assays
      • Cancer Cell Line Panel Screen
      • Biomarker Analysis
    • In Vitro Biology
      • Kinases
      • Epigenetics
      • GPCR, NR, Ion-channel, Transporter
      • Ubiquitin & PROTAC
      • KRAS
      • COVID-19
      • Radiometric
      • Customized assay development
      • High throughput screening
      • MOA Study
    • Metabolic & Cardiovascular Diseases
  • DMPK / Exploratory Toxicology
    • DMPK / Exploratory Toxicology
      • In vitro ADME
      • Pharmacokinetics
      • Exploratory Toxicology
      • Bioanalysis
      • Regulatory filing
    • Biomarkers, Preclinical & Clinical Sample Bioanalysis
    • Large molecule PK/BA services
      • Monoclonal Antibodies
      • Antibody Drug Conjugates
      • Bispecific Antibodies
      • Proteins & Peptides
      • Immunogenicity
  • Biologics Discovery
    • Antibody Discovery
      • Hybridoma
      • Antibody Engineering
      • Phage Display
      • Antibody-Drug Conjugate
    • Protein Science
    • Biologics Analytical Services
      • mAb Release Tests and Extended Characterization
      • Antibody-Drug Conjugate(ADC) Analysis
      • Therapeutic Protein Characterization
      • Biomolecular Interaction Analysis
    • B Cell Cloning
  • Biologics CMC
    • Stable Cell Line Development
    • Process Development
    • Formulation Development
    • Aseptic Filling and Freeze-drying
    • Drug Developability / Manufacturability study
    • Final Container Extractables & Leachables Study
    • Analytical Development and Testing
    • GMP Production
  • Small Molecule CMC
    • Process R&D Services
    • Process Safety
    • Analytical Development
    • Pre-Formulation Development
    • Formulation Development
    • ICH Stability Studies
    • CMC CTD Support
    • Manufacturing

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