Biomarkers, Preclinical & Clinical Sample Bioanalysis
Our state-of-the-art laboratories have the latest instrumentation such as G2-S QTof and API6500. Our internationally-trained scientists have developed more than 1000 methods for Discovery support and biomarker analysis. We have also developed extensive methods adhering to FDA guidelines for GLP or clinical sample analysis. We routinely add new analytical methods to support preclinical and clinical PK and biomarker studies of our Pharma and Biotech clients’ compounds discovered at ChemPartner. We also perform TK analysis in support of GLP preclinical safety assessments.
Using mass spectrometry, we routinely provide sample analysis for in vitro ADME and PK studies such as Metabolite ID, phenotyping of drug-metabolizing enzymes, assessments of P450 inhibition and induction, and PK evaluation in laboratory animals.