Biology & Pharmacology Archives | Page 4 of 5 | ChemPartner

Ex Vivo Analysis Platforms

<img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; 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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Ex Vivo Analysis Platforms

by cstolzerhy | Mar 5, 2021

Multi-color Flow Cytometry Luminex Quantigene ELISPOT

Ex Vivo Analysis Platforms

<img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; 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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Systemic inflammation in mice (Con A)

by Sarah Stapleton | Mar 5, 2021

Con-A Induced Systemic Inflammation in Mice Animal: BALB/c mice, female, 9-11 weeks Modeling: ConA (15 MPK) injection through tail veins Reference drug: Dexamethasone Readouts: Body weight, liver/spleen weight, ALT and AST level in serum, inflammatory cytokines...

Ex Vivo Analysis Platforms

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

IMQ induced psoriasis in mice

by Sarah Stapleton | Mar 5, 2021

Animal: BALB/c mice, female, 7.5 weeks Modeling: IMQ painted on shaved back skin daily Reference Drug: Tofacitinib, p.o., BID Readouts: Body weight, PASI score, skin thickness, pathology PASI Score Criterial: Erythema, scale, and thickness 0: no; 1: mild; 2: moderate;...

Ex Vivo Analysis Platforms

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Adjuvant induced arthritis in rats (AIA)

by Sarah Stapleton | Mar 5, 2021

Animal: Lewis rat, female, 180-200g Immunizations: CFA Readouts: body weight, joint swelling, clinical score, pathology, x-ray

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Autoimmune Disease and Inflammation In Vivo Models

by cstolzerhy | Mar 5, 2021

Respiratory Disease OVA-induced asthma in mice HDM-induced asthma in mice Bleomycin-induced lung fibrosis in mice Rheumatoid Arthritis Collagen-induced arthritis in rats (CIA) Adjuvant-induced arthritis in rats (AIA) Multiple Sclerosis (MS) MOG-induced EAE in mice...

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Th Subsets Differentiation (Th1/2/17/Treg) Assays

by Sarah Stapleton | Mar 5, 2021

Primary T Cell Differentiation Assay Species: human and mouse Type: Th1, Th2, Th17, Treg Cell Source: Naïve CD4+ T cell from hPBMC or mouse spleen tissue Th1: IFN-g+ Cells% by FACS Th17: IL-17a Conc. by ELISA Treg: CD25+Foxp3+ Cells% by FACS...

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

T Cells (Total, CD4+, CD8+) Activation and Proliferation Assays

by Sarah Stapleton | Mar 5, 2021

T Cell Activation Assay Customized Assay Format Cell Source: PBMC, CD3+ T, CD4+ T, CD8+ T Stimulation: TA in the presence or absence of anti-CD3/28, PHA, PMA, SEB Readout: Cell proliferation (CTG/FACS), cytokine release (ELISA/Luminex) ...

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Mixed Lymphocyte Reaction (MLR) Assay

by Sarah Stapleton | Mar 5, 2021

The MLR assay is considered the ‘gold standard’ T cell functional assay for the test of T cell immune checkpoint inhibitors Dendritic cells co-cultured with allogeneic CD3+ T cells Readouts: IFN-γ and IL-2 production Suitable to test both antibodies and small...

Ex Vivo Analysis Platforms

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img data-src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" width="1080" height="675" data-srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" data-sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" class="lazyload" style="--smush-placeholder-width: 1080px; --smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Whole Blood/PBMC Stimulation and Cytokine Release Assay

by Sarah Stapleton | Mar 5, 2021

LPS-induced Cytokine Release in Human PBMC

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--smush-placeholder-aspect-ratio: 1080/675;" /><noscript><img src="https://chempartner.com/wp-content/uploads/2021/02/BP--1080x669.png" alt="Ex Vivo Analysis Platforms" class="" width="1080" height="675" srcset="https://chempartner.com/wp-content/uploads/2021/02/BP--980x364.png 980w, https://chempartner.com/wp-content/uploads/2021/02/BP--480x178.png 480w" sizes="(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1080px, 100vw" />

Primary Immune Cell In Vitro Assays

by cstolzerhy | Mar 5, 2021

Whole Blood/PBMC Stimulation and Cytokine Release Assay Mixed Lymphocyte Reaction (MLR) Assay CMV Antigen Recall Assay Tumor/T Cell Co-culture Assay T Cells (Total, CD4+, CD8+) Activation and Proliferation Assays Th Subsets Differentiation (Th1/2/17/Treg) Assays Treg...

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