Blog
Common Preclinical ADC Development Mistakes (And How to Avoid Them)
Understanding the Complexities of Antibody-Drug Conjugate (ADC) Development Antibody-drug conjugates (ADCs) are at the forefront of targeted cancer therapies, offering a powerful combination of monoclonal antibody specificity and cytotoxic drug potency. However, ADC...
Employee Spotlight: Hu Liu, PhD
Employee Spotlight Our employee spotlight series celebrates the accomplishments and expertise of our valued scientists and staff. Hu Liu Hu Liu, PhD Director of Biologics Discovery Q&A with Dr. Liu What is your favorite part of your role here as Director of...
The Crucial Role of Cell Line Development in Fueling Therapeutic Advancements
In the dynamic world of biopharmaceutical research, cell line development and banking is pivotal in paving the way for groundbreaking therapies. Cell lines are stable cell cultures developed from a single cell, thus consisting of cells with a uniform genetic makeup....
Harnessing the Power of Antibody-Drug Conjugates (ADCs) with Expertise and CROs
In the ongoing battle against cancer, antibody-drug conjugates (ADCs) shine as a beacon of hope. These resourceful molecules combine the precision of monoclonal antibodies with the potency of cytotoxic drugs, making them a formidable weapon against drug resistance and...
Choosing the Right Antibody Generation Method: Phage Display, Hybridoma, or Single B Cell Cloning
There have been remarkable advancements in antibody generation technology over the years, offering scientists many techniques to generate antibodies for various applications ranging from discovery research to diagnostics and therapeutics. Three prominent methods for...
Employee Spotlight: Amy (Zichun) Wang, PhD
Employee Spotlight Our employee spotlight series celebrates the accomplishments and expertise of our valued scientists and staff. Amy (Zichun) Wang, PhD Amy (Zichun) Wang, PhD Senior Director of Cell Biology, Biology and Pharmacology Department Q&A with Amy What...
Equilibrium Dialysis vs. Ultracentrifugation for In Vitro Protein Binding Assays
In a modern drug discovery setting, in vitro protein binding assays are essential to assess the binding affinity and characteristics of a drug molecule with plasma proteins. Two commonly used methods for in vitro protein binding assays are equilibrium dialysis and...
In Vitro Safety Pharmacology: A Roadmap to Safer and More Effective Drugs
In vitro safety pharmacology profiling plays a crucial role in the drug development process by providing essential information about the potential safety and efficacy of new drug candidates. This approach involves conducting experiments in controlled laboratory...
3 Reasons to Introduce ADME Assays ASAP in Drug Discovery
Modern Drug Discovery Workflows There are several reasons why it is important to introduce in vitro absorption, distribution, metabolism, and excretion (ADME) assays as early as possible into a modern drug discovery workflow, especially for biotech companies. Here are...
In Vivo Intricacies: The Power of Orthotopic and Metastatic Models in Brain Tumor Studies
Brain tumors are a major cause of cancer-related death, and metastatic brain tumors are particularly difficult to treat. Brain tumors pose significant challenges to scientists in terms of understanding their development and progression, and finding effective treatment...
Employee Spotlight: Yan Wang, PhD
Employee Spotlight Our employee spotlight series celebrates the accomplishments and expertise of our valued scientists and staff. Yan Wang, PhD Yan Wang, PhD Director, Peptide Chemistry Q&A with Yan What is your favorite part of your role here as a Director of...
Employee Spotlight: Manny Ventura, PhD
Employee Spotlight Our employee spotlight series celebrates the accomplishments and expertise of our valued scientists and staff. Manny Ventura, PhD Manny Ventura, PhD Senior Director and Site Head at ChemPartner US Q&A with Manny What is your favorite part of...
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