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ChemPartner’s in vitro biology team has developed KRAS assays series for different screening strategies, which facilitate the identification of different types of inhibitors such as KRAS activity inhibitors and SOS1 activity inhibitors. We also conducted an in-depth study on the mechanism of inhibition.

KRAS Inhibitor Screening Strategy

KRAS Inhibitor and SOS1 Inhibitor

KRAS-SOS1 Activity Assay

The inhibitory effect of AMG-510 and BAY-293 on KRAS-wt, KRAS(G12C), & KRAS(G12D)


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Shanghai China, 201203


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