Case Studies in the Syngeneic Model

Efficacy Test in CT2.WT Model

Tumor Growth

Survival Evaluation (Endpoint: TV > 2000mm3

Mice under combination therapy exhibited survival benefit

Efficacy Test in 4T1 Resection Model

Tumors were resected on D13; Half mice to observe survival; another half taken down on D24 to evaluate tissue weight/metastasis

Survival Curve

(4T1 Resection Model)

Spleen Weight on Day 24

(4T1 Resection Model)

Lung Weight on Day 24

(4T1 Resection Model)

Lung Nodules Number on Day 24

(4T1 Resection Model)