Functional Assay Panels
ID Assay Type Cell Type 1 Mixed Lymphocyte Reaction (MLR) Primary human/mouse DC + T cells 2 CMV antigen recall Primary human T cells 3 T cell activation (anti-CD3/CD28) Primary human/mouse T cells 4 T cell activation (SEB super-antigen) Primary human T cells 5 T...
Luminex
Customized commercial kits Multiplexing with up to 80 analytes per well Validated Analytes Pool 253 Human targets 108 Mouse targets 104 Monkey targets 35 Rat targets QC Criterial Inner and inter-plate standard signal CV tracking Luminex Reader List 2D System Bio-Plex...
Multi-color Flow Cytometry
Multi-channel flow cytometer Customized panel design 96/384-well plate auto-sampler High-throughput screening Method development service Thermo Attune NxT Gentle MACS Dissociator Beckman...
Ex Vivo Analysis Platforms
Multi-color Flow Cytometry Luminex Quantigene ELISPOT
Systemic inflammation in mice (Con A)
Con-A Induced Systemic Inflammation in Mice Animal: BALB/c mice, female, 9-11 weeks Modeling: ConA (15 MPK) injection through tail veins Reference drug: Dexamethasone Readouts: Body weight, liver/spleen weight, ALT and AST level in serum, inflammatory cytokines...
IMQ induced psoriasis in mice
Animal: BALB/c mice, female, 7.5 weeks Modeling: IMQ painted on shaved back skin daily Reference Drug: Tofacitinib, p.o., BID Readouts: Body weight, PASI score, skin thickness, pathology PASI Score Criterial: Erythema, scale, and thickness 0: no; 1: mild; 2: moderate;...
Adjuvant induced arthritis in rats (AIA)
Animal: Lewis rat, female, 180-200g Immunizations: CFA Readouts: body weight, joint swelling, clinical score, pathology, x-ray
Autoimmune Disease and Inflammation In Vivo Models
Respiratory Disease OVA-induced asthma in mice HDM-induced asthma in mice Bleomycin-induced lung fibrosis in mice Rheumatoid Arthritis Collagen-induced arthritis in rats (CIA) Adjuvant-induced arthritis in rats (AIA) Multiple Sclerosis (MS) MOG-induced EAE in mice...