In-vitro ADME assays are critical for gaining insight into metabolism and potential drug interactions. Moving quickly through drug discovery and development saves you time and money. ChemPartner has industry-leading turnaround times for data to help our clients make risk-based decisions on the drug-like properties of hits and lead molecules quickly.
药物代谢稳定性及代谢产物测定
- 药物肝微粒体中的代谢稳定性试验
- 药物肝脏细胞中的代谢稳定性试验
- S9中的 代谢稳定性试验
- 血浆和全血中的代谢稳定性试验
- 药物代谢途径及代谢产物鉴定
药物-药物相互作用
- CYP450抑制实验
- CYP450诱导实验
- CYP450表型实验
药物分布
- • 血浆蛋白结合
- • 红细胞分配比
- • Caco-2 渗透性实验
- • MDCK MDR1 磁导率渗透性实验
- • MDCK BCRP 渗透性实验
理化特性
- • 溶解度和 Log D (pH7.4)
- • 化学稳定性
- • 粒径测定