Nucleoside, Nucleotide, and Nucleic Acid Chemistry
Nucleic acids (DNA) are the carriers of genetic information. The central dogma depicts that genetic information (genes) stored in DNA are transcribed into RNA which are then decoded to translate into proteins. A nucleic acid is an oligonucleotide sequence that is...
Carbohydrate Chemistry
Carbohydrate chemistry has been a specialized research area at ChemPartner since our founding. We have extensive expertise and solid experience in the synthesis of complex carbohydrates and their conjugates with a proven track record over the last twenty years....
ADC Services
ChemPartner has a comprehensive ADC (Antibody-Drug Conjugate) research and development platform and over a decade of experience. With a robust team specializing in linker-payload design synthesis, antibody discovery, and ADC conjugation as well as in vitro and in vivo...
In Vitro Pharmacology Safety Panel
An essential part of successful drug development is safety; therefore, many companies are now using safety pharmacology and profiling earlier in the drug discovery process to identify and mitigate off-target related adverse drug reactions and achieve optimal...肿瘤承载动物PK/PD研究
PK/PD Correlation in SU-DHL-6 CDX Phosphorylation of downstream target Y (PD marker) inversely correlated with the concentration of Compound X in the tumor (PK)CDX Models
SubcutaneousDisease# of ModelsModelsBladder Cancer4RT112; HT-1376; RT112 84; UM-UC-3 Breast Cancer14MDA-MB-231(x);MDA-MB-468(x2); MDA-MB-436; DU4475; HCC70; MX-1(TNBC total 6);MCF-7(x); ZR-75-1;BT-474(x); T-47D(x); HCC1569; HCC1954;...
MOA Study
In addition to assay development and compound profiling, ChemPartner’s in vitro biology team has the robust expertise related to the enzymology necessary to conduct in-depth research on the mechanism of action (MoA) for compounds, including reversibility studies,...
High Throughput Screening
ChemPartner’s possesses the world’s leading automated systems and provides customized high-throughput screening services for our clients. These services include the high-throughput biochemical/cellular assay development or assay validation, clients’ library compound...