In addition to assay development and compound profiling, ChemPartner’s in vitro biology team has the robust expertise related to the enzymology necessary to conduct in-depth research on the mechanism of action (MoA) for compounds, including reversibility studies, competition studies, and kinetic analysis (Ki, kon, koff, kinact determination).
Kinetic Analysis
Time-dependent Inhibition
Slow-off vs Irreversible Cmpds
Ki, kinact Determination
Modality of Inhibition
Competitive
Non-Competitive
Un-Competitive
