Neurodegeneration
- Alzheimer’s Disease – 5x Familial AD Transgenic Mice
- Biomarkers, pathology, EEG, behavioral tests, LTP in brain slice
- Parkinson’s Disease – 6-OHDA Rats
- Apomorphine or L-DOPA challenged rotation
- L-DOPA induced dyskinesia in 6-OHDA rats
- Reserpine-induced dyskinesia in rats
- Harmaline/tacrine-induced tremor in mice and rats
- Hearing Loss – Noise/Chemical-Induced
- Inner ear local delivery and sampling
- ABR tuning curve
- Frequency mapping
- Ophthalmic Degeneration Visible Light-induced Retinal Damage, Rodents
- Electroretinography (ERG)
Neuropsychiatry
- Depression
- Forced swim test, rats and mice
- Tail suspension, mice
- Anxiety
- Vogel conflict test, rats
- Marble test, mice
- Elevated plus maze, mice and rats
- Sucrose preference
- Sleep/Wake and Circadian Rhythm
- Polysomnograph
- Spontaneous Activity with vibration pattern recognition
- CNS Safety Pharmacology
- sLMA
- Modified Irwin
- Pharmaco-EEG in rodents and dogs
Pain
- Inflammatory Pain
- CFA-induced, rats
- Formalin-induced, rats
- Visceral Pain
- Acetic acid writhing, rodents
- Neuropathic Pain
- CCI
- SNL
- STZ-induced diabetic neuropathy
- Chemotherapy-induced neuropathy (Vincristine, Paclitaxel)
- Readouts
- Von Frey, Randall-Selito
- Tail flick, hot/cold plate
Epilepsy
- Chemically-induced seizure
- PTZ-induced, mice
- LiCl and pilocarpine-induced status epilepticus, rats
- Electrically-induced seizure
- 6 Hz electroshock-induced, mice
- Maximal electroshock-induced (MES), mice
- Maximal electroshock threshold (MEST), rodents
- Dravet mice: genetic seizure
Rare Disease
- MLD mice
- Twitcher mice
- Fabry mice
Automatic Analysis of Spontaneous Behavior
Laboras Measurement of Formalin-induced Pawlicks
Hindlimb Licking Number (Total)
AAV-GFP Targeted Expression in Cochlea of C57 Mice
Laser confocal scanning microscopy (LCSM)
Neuropathic Pain
CCl Model
Chung Model
