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PK/PD Study in Tumor Bearing Animal

by | Apr 6, 2021

PK/PD Correlation in SU-DHL-6 CDX Phosphorylation of downstream target Y (PD marker) inversely correlated with the concentration of Compound X in the tumor (PK)

CDX Models

by | Mar 30, 2021

SubcutaneousDisease# of ModelsModelsBladder Cancer4RT112; HT-1376; RT112 84; UM-UC-3 Breast Cancer14MDA-MB-231(x);MDA-MB-468(x2); MDA-MB-436; DU4475; HCC70; MX-1(TNBC total 6);MCF-7(x); ZR-75-1;BT-474(x); T-47D(x); HCC1569; HCC1954;...
MOA Study

MOA Study

by | Mar 5, 2021

In addition to assay development and compound profiling, ChemPartner’s in vitro biology team has the robust expertise related to the enzymology necessary to conduct in-depth research on the mechanism of action (MoA) for compounds, including reversibility studies,...
MOA Study

High Throughput Screening

by | Mar 5, 2021

ChemPartner’s possesses the world’s leading automated systems and provides customized high-throughput screening services for our clients. These services include the high-throughput biochemical/cellular assay development or assay validation, clients’ library compound...
MOA Study

Customized Assay Development

by | Mar 5, 2021

ChemPartner’s in vitro biology team has extensive experience in assay development and has the capability to provide a variety of customized assays for our customers.   Major Assay Technologies: Fluorescence Detection Chemiluminescence Detection FRET/TR-FRET...