Efficacy Test in CT2.WT Model Tumor Growth Survival Evaluation (Endpoint: TV > 2000mm3 Mice under combination therapy exhibited survival benefit Efficacy Test in 4T1 Resection Model Tumors were resected on D13; Half mice to observe survival;...
Mouse Clinical Trial in PDXs Objective: to evaluate drug efficacy across 17 colorectal PDXs Pre-defined Clinical Endpoints Tumor Progression A tumor volume change >73% by the end of treatement Tumor Stasis A tumor volume change between -66% and 73% by the end of...
Efficacy Study in CDXs Tumor Growth Inhibition in MV-4-11 Survival Rate in A375 Brain Inoculation Tumor Growth Inhibition in Hep3B 2.1-7 Efficacy and Biomarker Assessment in CDXs Cancer Discovery. 2018 Jul;8(7):836-849 Cell line derived allograft and xenograft models...
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