We offer multiple assay formats targeting the mAb portion, toxin, and the intact ADC drug. Single Intravenous Pharmacokinetics Study of Antibody Drug Conjugate (#1015) in Cynomolgus Monkey by Using Kadcyla® as Reference Target Mediated ADC Clearance in Cynomolgus...
Classical sandwich assay format was selected for epitope binning using Octet Red 384. About nine bins were generated based on the result. Classical Sandwich Assay Sandwich format requirement: Ag reach equilibrium in 5 minutes Disassociation of Ag <50% in 10 minutes...
KD measurement of peptide binding to target protein: kinetics, affinity. In the below case, more than 500 peptides were tested and the KD of which range from mM to nM. Positive Peptide Peptide A Peptide B
Immobilization Anti-hFc Capture Protein A Capture Protein G Capture High quality KD data can be obtained by various formats, such as: Anti-His Capture Anti-mFc Capture SA
Kinetics | Affinity | Thermodynamics How fast, strong & why… Is the binding of a lead antibody or compound? Specificity How specific & selective… Is this drug binding to its receptor? Concentration How much… Is the biologically active component in...
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