Efficacy Test in CT2.WT Model Tumor Growth Survival Evaluation (Endpoint: TV > 2000mm3 Mice under combination therapy exhibited survival benefit Efficacy Test in 4T1 Resection Model Tumors were resected on D13; Half mice to observe survival;...
Mouse Clinical Trial in PDXs Objective: to evaluate drug efficacy across 17 colorectal PDXs Pre-defined Clinical Endpoints Tumor Progression A tumor volume change >73% by the end of treatement Tumor Stasis A tumor volume change between -66% and 73% by the end of...
Efficacy Study in CDXs Tumor Growth Inhibition in MV-4-11 Survival Rate in A375 Brain Inoculation Tumor Growth Inhibition in Hep3B 2.1-7 Efficacy and Biomarker Assessment in CDXs Cancer Discovery. 2018 Jul;8(7):836-849 Cell line derived allograft and xenograft models...
ChemPartner has conducted thousands of in vitro and in vivo studies to deliver key data for clinical candidates in drug discovery programs for 100+ pharmaceutical and biotechnology companies worldwide. Based on the resource needed, our senior scientists can readily...
The tumor immunology platform at ChemPartner combines expertise from chemistry, biologics, DMPK and biology pharmacology, provides integrated services or functional services covering the broad scope of cancer immunotherapy drug discovery. Our Immuno-Oncology platform...
ChemPartner’s immunologists specialize in in vitro assays involving adoptive and innate immune responses with the use of various types of immune cells. Our team is highly experienced in the evaluation of immune cell activation/proliferation/differentiation, cytokine...
With strong scientific expertise and extensive ready-to-use models, our oncology team supports drug discovery for novel target validation, in vitro compound profiling, in vivo PKPD and efficacy studies, and translational medicine. An extensive panel of 800+ cancer...
Cell biology at ChemPartner combines scientific know-how with strong technical expertise to provide the best possible cell-based assay solutions to our customers. Over the past decade, we have built up an A-to-Z full spectrum platform cell-based assay platform to...
ChemPartner’s in vitro biology team has worked with hundreds of global pharmaceutical and biotechnology companies establishing, optimizing, and running assays. We have screened millions of compounds and generated extensive, quality data for our customers. Our team of...
