Luminex

Luminex

Customized commercial kits Multiplexing with up to 80 analytes per well Validated Analytes Pool 253 Human targets 108 Mouse targets 104 Monkey targets 35 Rat targets QC Criterial Inner and inter-plate standard signal CV tracking Luminex Reader List 2D System Bio-Plex...
Luminex

Multi-color Flow Cytometry

Multi-channel flow cytometer Customized panel design 96/384-well plate auto-sampler High-throughput screening Method development service     Thermo Attune NxT   Gentle MACS Dissociator   Beckman...
Ex Vivo Analysis Platforms

Systemic inflammation in mice (Con A)

Con-A Induced Systemic Inflammation in Mice Animal: BALB/c mice, female, 9-11 weeks Modeling: ConA (15 MPK) injection through tail veins Reference drug: Dexamethasone Readouts: Body weight, liver/spleen weight, ALT and AST level in serum, inflammatory cytokines...
Ex Vivo Analysis Platforms

IMQ induced psoriasis in mice

Animal: BALB/c mice, female, 7.5 weeks Modeling: IMQ painted on shaved back skin daily Reference Drug: Tofacitinib, p.o., BID Readouts: Body weight, PASI score, skin thickness, pathology PASI Score Criterial: Erythema, scale, and thickness 0: no; 1: mild; 2: moderate;...
Ex Vivo Analysis Platforms

Autoimmune Disease and Inflammation In Vivo Models

Respiratory Disease OVA-induced asthma in mice HDM-induced asthma in mice Bleomycin-induced lung fibrosis in mice Rheumatoid Arthritis Collagen-induced arthritis in rats (CIA) Adjuvant-induced arthritis in rats (AIA) Multiple Sclerosis (MS) MOG-induced EAE in mice...
Ex Vivo Analysis Platforms

Th Subsets Differentiation (Th1/2/17/Treg) Assays

Primary T Cell Differentiation Assay Species: human and mouse Type: Th1, Th2, Th17, Treg Cell Source: Naïve CD4+ T cell from hPBMC or mouse spleen tissue   Th1: IFN-g+ Cells% by FACS   Th17: IL-17a Conc. by ELISA   Treg: CD25+Foxp3+ Cells% by FACS...
Ex Vivo Analysis Platforms

Mixed Lymphocyte Reaction (MLR) Assay

The MLR assay is considered the ‘gold standard’ T cell functional assay for the test of T cell immune checkpoint inhibitors Dendritic cells co-cultured with allogeneic CD3+ T cells Readouts: IFN-γ and IL-2 production Suitable to test both antibodies and small...