Outsourcing Chiral Separations

Outsourcing Chiral Separations

It is critical to isolate unique isomers for targeted structural design and accurate assay readouts in small molecule development. Chiral intermediate or final compound single enantiomer isolation is necessary for key assays. Where chiral synthesis is challenging or...
Advancements in Plasma Cell Biology

Advancements in Plasma Cell Biology

A recently published article entitled Ex vivo engineered human plasma cellsexhibit robust protein secretion and long-term engraftment in vivo1 shows that a subset of in vitro cultured plasma B cells can take on characteristics of long-lived natural plasma B cells. Due...
How Does Remdesivir Work?

How Does Remdesivir Work?

Gileadʹs antiviral drug remdesivir has been catapulted to the limelight as the only FDA-approved treatment of coronavirus Covid-19 for emergency use thus far. On April 29, 2020, preliminary clinical trials indicated that the drug has shown some efficacy. While...
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