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New Publications Review: Medicinal and Organic Chemistry
This blog series presents links to new literature on topics of Medicinal and Organic Chemistry. It is derived from surveys of the Table of Contents for the Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of Organic Chemistry, Journal of the...
New Publications Review: Medicinal and Organic Chemistry
This blog series presents links to new literature on topics of Medicinal and Organic Chemistry. It is derived from surveys of the Table of Contents for the Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of Organic Chemistry, Journal of the...
New Publications Review: Medicinal and Organic Chemistry
This blog series presents links to new literature on topics of Medicinal and Organic Chemistry. It is derived from surveys of the Table of Contents for the Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of Organic Chemistry, Journal of the...
New Publications Review: Medicinal and Organic Chemistry
This blog series presents links to new literature on topics of Medicinal and Organic Chemistry. It is derived from surveys of the Table of Contents for the Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of Organic Chemistry, Journal of the...
Benefits of Working with a CDMO
The combined small and large molecule Contract Development and Manufacturing Organization (CDMO) market was valued at $52.8 billion dollars in 2021 with annual growth rates of 6.5% and 8.6% (respectively) from 2022 to 2030. So, why are more and more biotech and...
New Publications Review: Medicinal and Organic Chemistry
This blog series presents links to new literature on topics of Medicinal and Organic Chemistry. It is derived from surveys of the Table of Contents for the Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of Organic Chemistry, Journal of the...
New Publications Review: Medicinal and Organic Chemistry
This blog series presents links to new literature on topics of Medicinal and Organic Chemistry. It is derived from surveys of the Table of Contents for the Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, Journal of Organic Chemistry, Journal of the...
Happy Mid-Autumn Festival
With popularity on par with Chinese New Year, the Mid-Autumn Festival is one of the most important holidays in Chinese culture and is celebrated all over the world during the full moon between September and October. Festival Origin Over 3,000 years ago, during the...
Antibody Generation: Single B Cell Cloning vs. Hybridoma
PD-L1 is a key inhibitor of T cell activation that is often over-expressed in cancer to escape immune surveillance and promote tumor progression. Blocking antibodies against PD-L1 or its receptor, PD-1, have shown significant clinical benefit in some patients with...
How Is Remdesivir Made?
Gileadʹs antiviral drug remdesivir (Veklury, 1) was approved by the FDA on May 1st for emergency use against coronavirus disease-2019 (COVID-19) after just a one-day review. Now the onerous task falls upon Gilead to make enough of the drug to supply doctors and...
Discovery of the Hepatitis C Virus — The 2020 Nobel Prize in Physiology or Medicine
On October 5, 2020, the Nobel Assembly at the Karolinska Institute announced the Nobel Prize for Physiology or Medicine went to Harvey J. Alter, Michael Houghton, and Charles M. Rice “for their discovery of hepatitis C virus (HCV).” The worldwide incidence of HCV...
How Does Remdesivir Work?
Gileadʹs antiviral drug remdesivir has been catapulted to the limelight as the only FDA-approved treatment of coronavirus Covid-19 for emergency use thus far. On April 29, 2020, preliminary clinical trials indicated that the drug has shown some efficacy. While...
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