ChemPartner’s antibody engineering team performs antibody sequencing and chimeric antibody generation routinely. Supported by an elite protein structure team in modeling area, we are able to do hotspot analysis and removal, world-class humanization design with consideration of activity, immunogenicity, and developability. By working closely with our biologics analytical team, we ensure our clients get high throughput characterization and short turnaround times with guaranteed affinities and functional activities.
Since the establishment of the antibody engineering platform, we have completed more than 50 humanization projects. The successful rate of achieving humanized antibody binding affinity close to that of the parental mouse monoclonal antibody is close to 100%.