In-vitro ADME assays are critical for gaining insight into metabolism and potential drug interactions. Moving quickly through drug discovery and development saves you time and money. ChemPartner has industry-leading turnaround times for data to help our clients make risk-based decisions on the drug-like properties of hits and lead molecules quickly.
Metabolic Stability and Metabolite Identification
- Liver microsomes
- Hepatocytes
- Liver S9 fractions
- Plasma and whole blood
- Metabolic pathway and metabolites identification
Drug-Drug Interactions
- CYP450 inhibition
- CYP450 induction
- CYP450 phenotyping
Distribution
- Plasma protein binding
- Blood partitioning
- Caco-2 permeability
- MDCK MDR1 permeability
- MDCK BCRP permeability
Physical Chemical Properties
- Solubility and Log D (pH7.4)
- Chemical stability
- Particle size
